Aneuploidy
Tags
Biology
Cegep/1
Word count
87 words
Reading time
1 minute
Numerical chromosome abnormality, i.e. atypical number of chromosomes
Frequency of aneuploid zygotes in human is 10-25%.
Types
Monosomy
One less chromosome (2n - 1)
Often lethal
[!abstract] Turner syndrome: X0, phenotypically female, sterile
Trisomy
One more chromosome (2n + 1)
Often harmful
[!example] Down syndrome (trisomy 21): 3 21th chromosomes
[!example] Klinefelter syndrome: XXY, often sterile, small testicles
[!example] XYY syndrome: no syndrome
[!example] Trisomy X: XXX, mostly no syndrome
Don't look up trisomy 13...
Ajitani Hifumi